Wednesday, 8 June 2005

Princess Health and Local "Naturopathic Doctor" Shut Down. Princessiccia

Princess Health and Local "Naturopathic Doctor" Shut Down. Princessiccia

Our own Providence Journal reported that the RI Health Department shut down the office of a "naturopathic doctor," John E. Curran, after federal agents raided two of his offices. Before reading the news article, it's instructive to look at Curran's web-site, which was still up, at least through today.
On it he:
  • claims he can treat "catastrophic" or "unusual or rare" diseases;
  • implies that his treatments are harmless, and, in comparison to standard medicine, "Treatments are more natural, gentler, and more easily accepted by our bodies;"
  • implies he is a licensed ND, naturopathic doctor;
  • claims that his version of naturopathy is "evidence-based;" and
  • provides a testimonial of a patient who seems to say that Curran put his Stage 4 head and neck cancer into remission.
The Providence Journal reported that Curran is under federal investigation for wire fraud, mail fraud, and money laundering. The order to shut down his office came after a patient with liver disease was "sickened" by an alcohol based medicine that Curran prescribed. Undercover agents who visited Curran were subjected to a "live blood analysis," which Curran said revealed "parasites" in their blood, or malformed blood cells; and a "biomeridian stress assessment." The treatments Curran proposed for these problems would cost about $10,000.
Curran's practice is listed on a this web-site which has links to a variety of New England based "holistic" practitioners. Some make claims to treat real diseases that seem far from evidence based, for example:
And the claims found on the web-site for the Tai Sophia Institute, the organization that recently announced a formal collaboration with the University of Pennsylvania Medical School, are only somewhat less sweeping (see our previous posts here and here.)
At a time when health care is derided for its rising costs, declining accessibility to patients, and stagnant quality, I wonder why do there is so little concern about the costs incurred by these so-called complementary and alternative medicine practitioners, and so little skepticism about the expansive claims they make about the tests and treatments they provide?
Princess Health and  Local "Naturopathic Doctor" Shut Down.Princessiccia

Princess Health and Local "Naturopathic Doctor" Shut Down.Princessiccia

Our own Providence Journal reported that the RI Health Department shut down the office of a "naturopathic doctor," John E. Curran, after federal agents raided two of his offices. Before reading the news article, it's instructive to look at Curran's web-site, which was still up, at least through today.
On it he:
  • claims he can treat "catastrophic" or "unusual or rare" diseases;
  • implies that his treatments are harmless, and, in comparison to standard medicine, "Treatments are more natural, gentler, and more easily accepted by our bodies;"
  • implies he is a licensed ND, naturopathic doctor;
  • claims that his version of naturopathy is "evidence-based;" and
  • provides a testimonial of a patient who seems to say that Curran put his Stage 4 head and neck cancer into remission.
The Providence Journal reported that Curran is under federal investigation for wire fraud, mail fraud, and money laundering. The order to shut down his office came after a patient with liver disease was "sickened" by an alcohol based medicine that Curran prescribed. Undercover agents who visited Curran were subjected to a "live blood analysis," which Curran said revealed "parasites" in their blood, or malformed blood cells; and a "biomeridian stress assessment." The treatments Curran proposed for these problems would cost about $10,000.
Curran's practice is listed on a this web-site which has links to a variety of New England based "holistic" practitioners. Some make claims to treat real diseases that seem far from evidence based, for example:
And the claims found on the web-site for the Tai Sophia Institute, the organization that recently announced a formal collaboration with the University of Pennsylvania Medical School, are only somewhat less sweeping (see our previous posts here and here.)
At a time when health care is derided for its rising costs, declining accessibility to patients, and stagnant quality, I wonder why do there is so little concern about the costs incurred by these so-called complementary and alternative medicine practitioners, and so little skepticism about the expansive claims they make about the tests and treatments they provide?

Monday, 6 June 2005

Princess Health and Allegations That Merck Threatened Researchers Who Expressed Doubts About Vioxx. Princessiccia

Princess Health and Allegations That Merck Threatened Researchers Who Expressed Doubts About Vioxx. Princessiccia

The Philadelphia Inquirer reported a series of allegations that a top Merck executive threatened and intimidated physicians who questioned the safety of its Cox-2 inhibitor drug Vioxx, now off the market.
Louis M. Sherwood, who retired as a Senior Vice President of Medical and Scientific Affairs for Merck, had been known as "the epitome of an upstanding guy, smart and well-respected." The Inquirer reported that "Sherwood earned accolades from both worlds [academia and industry]. At retirement in March 2002, he was given two lifetime achievement awards, one from industry physicians and one from medical-schol professors."
Nonetheless, evidence discovered in one of the cases against Merck revealed:
  • Lee Simon, a former Harvard faculty member, after lecturing about the risks of Vioxx, said he was threatened by Sherwood: "he would hurt my career if I continued to lecture." Sherwood also charged that Simon was biased against Vioxx. However, the Inquirer reported that Simon's "boss at Harvard, Steven Weinberger, now a Vice-President at the American College of Physicians in Philadelphia, confirmed getting Sherwood's call but said it had 'nothing to do' with Simon's promotion." Weinberger stated, "Lou Sherwood was not at all threatening me." Yet, John Yates, Sherwood's successor at Merck, contacted Simon, and said, according to him, that Sherwood's behavior "would never happen again, that it was unnecessary, that it was not the behavior of Merck." [Note that Dr. Weinberger has appeared in Health Care Renewal posts in the past, here, here, and here, on the subject of declining interest in primary care, which he has suggested is due more to shortcomings in how medical schools promote the field to students and due to inadequate current "chronic care models" than to pressures faced by practicing physicians, including external threats to their core values.]
  • M. Thomas Stillman, from the University of Minnesota Medical School, also questioned the safety of Vioxx. A Merck "sales executive" described him as a "vocal adversary of Merck and Vioxx" in an email. A memo documented that Sherwood had "complained to Stillman's boss." Yates also called Stillman to apologize.
  • Gurkirpal Singh, from Stanford University, questioned whether data about Vioxx was being hidden. A memo by Sherwood described Singh as "perceived as an advocate for Searle," which was then the manufacturer of the competing drug, Celebrex. The Inquirer reported that Sherwood called Singh's supervisor, Professor James F. Fries, at home, labeled Singh "anti-Vioxx," suggested Singh would "flame out," and threatened Fries with "consequences for myself and for Stanford," according to Fries. Fries wrote Merck to complain, noting all the above cases and those of two other researchers. Fries then got a call from David Anstice, President of the Human Health-Americas division of Merck, saying that Sherwood's behavior was "not the norm," and promising to take action.
These are serious allegations, involving apparent efforts by a pharmaceutical company to stifle free speech and academic freedom to suppress unfavorable comments about the company's products. Such behaviors threaten core academic and scientific values. If physicians and researchers cannot openly discuss scientific findings, science will not advance. If they cannot openly discuss possible harms to patients, patients may be harmed.
Unfortunately, if these allegations are true, they will become just another entry in the sorry catalog of threats to free speech and academic freedom in medicine, (which may relate to the many threats to free speech and academic freedom in colleges and universities, such as those that have been documented by FIRE.)
Physicians and scientists must learn how to defend themselves against such threats, or science, and worse, patients will suffer.
Princess Health and  Allegations That Merck Threatened Researchers Who Expressed Doubts About Vioxx.Princessiccia

Princess Health and Allegations That Merck Threatened Researchers Who Expressed Doubts About Vioxx.Princessiccia

The Philadelphia Inquirer reported a series of allegations that a top Merck executive threatened and intimidated physicians who questioned the safety of its Cox-2 inhibitor drug Vioxx, now off the market.
Louis M. Sherwood, who retired as a Senior Vice President of Medical and Scientific Affairs for Merck, had been known as "the epitome of an upstanding guy, smart and well-respected." The Inquirer reported that "Sherwood earned accolades from both worlds [academia and industry]. At retirement in March 2002, he was given two lifetime achievement awards, one from industry physicians and one from medical-schol professors."
Nonetheless, evidence discovered in one of the cases against Merck revealed:
  • Lee Simon, a former Harvard faculty member, after lecturing about the risks of Vioxx, said he was threatened by Sherwood: "he would hurt my career if I continued to lecture." Sherwood also charged that Simon was biased against Vioxx. However, the Inquirer reported that Simon's "boss at Harvard, Steven Weinberger, now a Vice-President at the American College of Physicians in Philadelphia, confirmed getting Sherwood's call but said it had 'nothing to do' with Simon's promotion." Weinberger stated, "Lou Sherwood was not at all threatening me." Yet, John Yates, Sherwood's successor at Merck, contacted Simon, and said, according to him, that Sherwood's behavior "would never happen again, that it was unnecessary, that it was not the behavior of Merck." [Note that Dr. Weinberger has appeared in Health Care Renewal posts in the past, here, here, and here, on the subject of declining interest in primary care, which he has suggested is due more to shortcomings in how medical schools promote the field to students and due to inadequate current "chronic care models" than to pressures faced by practicing physicians, including external threats to their core values.]
  • M. Thomas Stillman, from the University of Minnesota Medical School, also questioned the safety of Vioxx. A Merck "sales executive" described him as a "vocal adversary of Merck and Vioxx" in an email. A memo documented that Sherwood had "complained to Stillman's boss." Yates also called Stillman to apologize.
  • Gurkirpal Singh, from Stanford University, questioned whether data about Vioxx was being hidden. A memo by Sherwood described Singh as "perceived as an advocate for Searle," which was then the manufacturer of the competing drug, Celebrex. The Inquirer reported that Sherwood called Singh's supervisor, Professor James F. Fries, at home, labeled Singh "anti-Vioxx," suggested Singh would "flame out," and threatened Fries with "consequences for myself and for Stanford," according to Fries. Fries wrote Merck to complain, noting all the above cases and those of two other researchers. Fries then got a call from David Anstice, President of the Human Health-Americas division of Merck, saying that Sherwood's behavior was "not the norm," and promising to take action.
These are serious allegations, involving apparent efforts by a pharmaceutical company to stifle free speech and academic freedom to suppress unfavorable comments about the company's products. Such behaviors threaten core academic and scientific values. If physicians and researchers cannot openly discuss scientific findings, science will not advance. If they cannot openly discuss possible harms to patients, patients may be harmed.
Unfortunately, if these allegations are true, they will become just another entry in the sorry catalog of threats to free speech and academic freedom in medicine, (which may relate to the many threats to free speech and academic freedom in colleges and universities, such as those that have been documented by FIRE.)
Physicians and scientists must learn how to defend themselves against such threats, or science, and worse, patients will suffer.
Princess Health and Bristol-Myers-Squibb Settling Case of Inflated Sales Figures. Princessiccia

Princess Health and Bristol-Myers-Squibb Settling Case of Inflated Sales Figures. Princessiccia

The NY Times reported that Bristol-Myers-Squibb will soon be paying about $300 million in exchange for the US Department of Justice deferring prosecution of its alleged criminal conduct. The allegations were that the company inflated sales figures that it reported to investors. The company's current CEO, Peter R. Dolan, has acknowledged that the company inflated revenue by about $2.5 billion from 1999 to 2002. (See this Forbes article for more on Dolan's record.)
Princess Health and  Bristol-Myers-Squibb Settling Case of Inflated Sales Figures.Princessiccia

Princess Health and Bristol-Myers-Squibb Settling Case of Inflated Sales Figures.Princessiccia

The NY Times reported that Bristol-Myers-Squibb will soon be paying about $300 million in exchange for the US Department of Justice deferring prosecution of its alleged criminal conduct. The allegations were that the company inflated sales figures that it reported to investors. The company's current CEO, Peter R. Dolan, has acknowledged that the company inflated revenue by about $2.5 billion from 1999 to 2002. (See this Forbes article for more on Dolan's record.)
Princess Health and More on the Alliance Between the University of Pennsylvania and the Tai Sophia Institute. Princessiccia

Princess Health and More on the Alliance Between the University of Pennsylvania and the Tai Sophia Institute. Princessiccia

The Associated Press has done a follow-up of the new relationship between the University of Pennsylvania Medical School and the Tai Sophia Institute, "an alternative medicine school." (See our previous post here.)
The new article quoted the leader of Tai Sophia, "the goal is that the Penn medical school graduates will be highly able to speak with patients about how to guide these things [acupuncture, herbalism] in overall care."
Furthermore, Dr. Alfred P Fishman, "co-director of the collaboration," noted, "today, we're moving away from being completely focused on preventing disease and toward looking at what it takes to [achieve and maintain] wellness... I think patient care will improve enormously."
In particular, the article reported that "cardiologists at Penn's Presbyterian Medical Center are working with Tai Sophia to integrate alternative therapies into traditional care for heart patients. The idea is to teach the cardiology staff how to develop personalized therapy plans - including everything from meditation and message to reflexology and aromatherapy - to decrease patient stress, pain and anxiety."
However, the article also included a riposte by Steven Barrett, who runs Quackwatch. Barrett charged that alternative medicine is not being accepted into medical schools because of good evidence that it works, but because "skeptical voices are squelched and 'administrators see it as a way to jump on the bandwagon and get grant money.'"
I wonder what sort of data exists on the benefits of reflexology or aromatherapy for patients with heart disease? I would bet not much. Quick PubMed searches did not reveal anything convincing. For Quackwatch's take, see their page on reflexology, and their page on aromatherapy.
I am still waiting for any rationale for the University of Pennsylvania's embrace of the Tai Sophia Institute that fits with the University's scientific mission.